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Patients who are receiving medications to suppress the immune system in the treatment of some other condition may be allowed to temporarily decrease the medications in order to allow the immune system to combat the infection and recover from the anemia. Those with weakened (not suppressed) immune systems, such as AIDS patients, may be given immunoglobulin intravenously to help the immune system fight the infection. People with severe anemia or who experience an aplastic crisis may require hospitalization and blood transfusions..