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As I was sitting there bowling my second game, I saw a gaggle of large people wander through the bowling alley. Right next to me was Julius Thomas, who when I yelled “Orange Julius!” stopped and shook my hand and said hi. We were also able to find some other Broncos in the bar area that weren advertised as coming, including Knowshon Moreno. amazon.com zi xiu tang Polycystic ovarian syndrome (PCOS) is a condition affecting women that causes various symptoms including obesity, male pattern hair growth, a lack of periods and infertility. It is thought that a high level of insulin leads to the persistence of immature egg follicles1 in the ovaries, leading to excess production of male hormones. It is these multiple follicles that give the disease its name ‘polycystic’2 is, in a sense, a misnomer. The condition occurs in 5 10% of women in their reproductive years, though it does not always cause symptoms. Furthermore, one in five women who menstruate normally will have large numbers of follicles in their ovaries, but two thirds of these women will not have PCOS. These hormones act on two types of cell in the egg follicle: LH causes the thecal cells to produce weak androgens, and FSH causes the granulosa cells to convert the androgens into oestrogens. It is thought that a high level of insulin in the blood due to insulin resistance3 can prevent the death of the thecal cells, with the result that instead of being released at ovulation4, the egg follicles remain in the ovary. The retained follicles lose their granulosa cells, with the result that the weak androgens made by the thecal cells are converted into testosterone instead. As oestrogen production falls, the pituitary produces more LH in an attempt to increase weak androgen and thus oestrogen production, but this simply results in the production of more testosterone.
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